We are entering a new economy and business model with tremendous potential for Human Resources to lead strategic organizational success. However, your business is facing five threats for survival. HR must be ready to anticipate, respond, adapt, and above all, lead through these critical threats. The old economy was embodied by large companies facing limited competition in stable markets. The new economy is fueled by the fast eating the slow. The facts are alarming and CEOs are turning to HR to lead this organizations through these five threats and mine fields. We will discuss how today’s organizational success is solely in the hands of Human Resources.